Quinolines and derivatives
Ambeed tertButyl 1 8diazaspiro 4.5 de
tert-Butyl 1,8-diazaspiro[4.5]decane-8-carboxylate, 937729-06-1, 95%
eMolecules 36404-88-3 | 2-CHLORO-PYRIDINE-3-CARBALDEHYDE | AstaTech | MFCD01315308 | 141.550 | C6H4ClNO | 97.000 | Clc1ncccc1C=O | 25g | 112525679
2-CHLORO-PYRIDINE-3-CARBALDEHYDE | AstaTech | 36404-88-3 | MFCD01315308 | 141.550 | C6H4ClNO | 97.000 | Clc1ncccc1C=O | 25g | 112525679
eMolecules 74124-79-1 | N,N'-Disuccinimidyl carbonate | Chem-Impex | MFCD00009767 | 256.170 | C9H8N2O7 | 99.000 | O=C(ON1C(=O)CCC1=O)ON1C(=O)CCC1=O | 250g | 112443064
N,N'-Disuccinimidyl carbonate | Chem-Impex | 74124-79-1 | MFCD00009767 | 256.170 | C9H8N2O7 | 99.000 | O=C(ON1C(=O)CCC1=O)ON1C(=O)CCC1=O | 250g | 112443064
![Medchemexpress LLC 3-piperidinecarboxamide, 1-(cyclopropylmethyl)-4-[[[5-(2,4-difluorophenyl)-3-isoxazolyl]carbonyl]am | 2178049-58-4 | 98.8% | 522.55 | C27H28F2N6O3 | 5 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000221277.png-250.jpg)
Medchemexpress LLC 3-piperidinecarboxamide, 1-(cyclopropylmethyl)-4-[[[5-(2,4-difluorophenyl)-3-isoxazolyl]carbonyl]am | 2178049-58-4 | 98.8% | 522.55 | C27H28F2N6O3 | 5 MG
ACT-1004-1239 is a potent, selective, orally active CXCR7 (ACKR3) antagonist supplied for research use. It shows nanomolar potency in biochemical assays and has demonstrated target engagement and pharmacological effects in preclinical models, including modulation of CXCL12/CXCL11 signaling and efficacy in rodent disease models. Supplied formats support both in vitro and in vivo study designs.
- Potent CXCR7 antagonism with reported IC50 of 3.2 nM.
- High purity suitable for research applications.
- Available as solid and 10 mM DMSO solution for convenient use.
- Appropriate for in vitro and in vivo pharmacology studies.
- For research use only; not for human or veterinary use.
Medchemexpress LLC 6PPD-Q | 2754428-18-5 | C18H22N2O2 | 100 MG
6PPD-Q | 2754428-18-5 | C18H22N2O2 | 100 MG
Medchemexpress LLC PI3K-IN-31 | 1359956-12-9 | 99.3% | 435.43 g/mol | C19H23F2N7O3 | 5 MG
PI3K-IN-31 is a small-molecule PI3K inhibitor for research use, showing potent activity across class I PI3K isoforms and reported anticancer effects. Supplied as a high-purity solid or as a DMSO solution, it is intended for preclinical and signaling studies in oncology research.
- Potent multi-isoform PI3K inhibition: PI3Kα 3.7 nM; PI3Kβ 74 nM; PI3Kγ 14.6 nM; PI3Kδ 9.9 nM.
- High purity: 99.33%.
- Available formats: solid (5, 10, 25, 50, 100 mg) and 10 mM solution in DMSO.
- C hemical formula C19H23F2N7O3; molecular weight 435.43 g/mol.
- Recommended storage: powder -20°C (3 years) or 4°C (2 years); in solvent -80°C (6 months) or -20°C (1 month).
eMolecules 5622-36-6 | methyl 2-(quinolin-6-yl)acetate | Pharmablock - Stock | MFCD04038669 | 201.225 | C12H11NO2 | 97.000 | COC(=O)Cc1ccc2ncccc2c1 | 5g | 415696919
methyl 2-(quinolin-6-yl)acetate | Pharmablock - Stock | 5622-36-6 | MFCD04038669 | 201.225 | C12H11NO2 | 97.000 | COC(=O)Cc1ccc2ncccc2c1 | 5g | 415696919
eMolecules 5622-36-6 | methyl 2-(quinolin-6-yl)acetate | Pharmablock - Stock | MFCD04038669 | 201.225 | C12H11NO2 | 97.000 | COC(=O)Cc1ccc2ncccc2c1 | 1g | 415696918
methyl 2-(quinolin-6-yl)acetate | Pharmablock - Stock | 5622-36-6 | MFCD04038669 | 201.225 | C12H11NO2 | 97.000 | COC(=O)Cc1ccc2ncccc2c1 | 1g | 415696918
eMolecules 21635-88-1 | oxetan-3-amine | Pharmablock | MFCD08544363 | 73.095 | C3H7NO | 97.000 | NC1COC1 | 250mg | 551053875
oxetan-3-amine | Pharmablock | 21635-88-1 | MFCD08544363 | 73.095 | C3H7NO | 97.000 | NC1COC1 | 250mg | 551053875
eMolecules 36404-88-3 | 2-CHLORO-PYRIDINE-3-CARBALDEHYDE | AstaTech | MFCD01315308 | 141.550 | C6H4ClNO | 97.000 | Clc1ncccc1C=O | 100g | 206680064
2-CHLORO-PYRIDINE-3-CARBALDEHYDE | AstaTech | 36404-88-3 | MFCD01315308 | 141.550 | C6H4ClNO | 97.000 | Clc1ncccc1C=O | 100g | 206680064
Medchemexpress LLC Amino-PEG3-C2-amine | 929-75-9 | MFCD00628164 | 98.0% | 192.26 g/mol | C8H20N2O3 | 10 G
Amino-PEG3-C2-Amine is a PEG-based linker containing three ethylene glycol units and a terminal primary amine. It functions as a flexible spacer for assembling proteolysis targeting chimera (PROTAC) molecules and other bioconjugates, offering aqueous solubility and a reactive amine handle for downstream coupling and functionalization in synthetic workflows.
- PEG-based spacer with three ethylene glycol units.
- Terminal primary amine for straightforward conjugation.
- Improves solubility and reduces steric hindrance in constructs.
- Molecular weight 192.26 g/mol for predictable stoichiometry.
- Suitable for PROTAC synthesis and other bioconjugation applications.
- Available in multiple laboratory-scale packaging options.
Medchemexpress LLC MYF-03-176 | 2857937-59-6 | 99.72% | 410.37 | 25 MG
MYF-03-176 is an orally active inhibitor of TEAD, suppressing TEAD transcriptional activity with an IC50 of 11 nM. It inhibits hippo signaling defective malignant pleural mesothelioma (MPM) cells and demonstrates strong antitumor efficacy in an MPM mouse xenograft model. The IC50 values for TEAD1, TEAD3, and TEAD4 are 47, 32, and 71 nM, respectively.
- Orally active inhibitor of TEAD
- Suppresses TEAD transcriptional activity with an IC50 of 11 nM
- Inhibits hippo signaling defective malignant pleural mesothelioma (MPM) cells
- Demonstrates strong antitumor efficacy in MPM mouse xenograft model
Medchemexpress LLC Sri 6409-94 | 127697-58-9 | 99.3% | 379.49 | 25 MG
SRI 6409-94 is an orally active Ro 13-6298 analogue that is teratogenic. It serves as a molecular tool to study the effect of the three-dimensional configuration of retinol on teratogenic activity.
- Orally active Ro 13-6298 analogue
- Teratogenic
- Molecular tool for studying retinol's three-dimensional configuration and teratogenic activity
- Causes deformed offspring in a dose-dependent manner in virgin female outbred Syrian golden hamsters
- Leads to significant reductions in mean fetal body weight and in the numbers of ossified skeletal districts